No photo description available.

Ham and Cheese Biscuit Sliders: A Warm, Cheesy Crowd-Pleasing Recipe

Ham and cheese biscuit sliders are the kind of easy comfort food that can turn a handful of simple ingredients into something everyone reaches for. Soft, buttery biscuits are filled with savory ham and melty cheese, then brushed with a flavorful butter topping before being baked until golden and bubbling.

These sliders are especially useful when you need a quick breakfast, an easy lunch, a party appetizer, or a make-ahead dish for a gathering. The combination of salty ham, creamy melted cheese, tender biscuits, and a buttery, slightly seasoned topping makes every bite satisfying without requiring complicated cooking techniques.

The best part is that the sliders can be customized. You can switch the cheese, add a little mustard, include scrambled eggs for breakfast, or give the butter topping a different flavor depending on what you have in the kitchen.

Why You’ll Love These Ham and Cheese Biscuit Sliders

There are several reasons this recipe is worth keeping in your recipe collection:

Simple ingredients: You only need a few everyday ingredients.
Quick preparation: Assembly takes just a few minutes.
Great for groups: One baking dish produces several individual sliders.
Easy to customize: Change the cheese, seasonings, or fillings to suit your taste.
Make-ahead friendly: The sandwiches can be assembled before baking.
Perfectly comforting: Warm biscuits and gooey cheese make an irresistible combination.

Ingredients You’ll Need

For approximately 12 sliders, gather:

For the Sliders

1 package of 12 soft dinner rolls or small biscuits
12 slices of ham
6–8 slices of Swiss, cheddar, provolone, or mozzarella cheese
2 tablespoons Dijon or yellow mustard, optional
2 tablespoons mayonnaise, optional

For the Butter Topping

4 tablespoons unsalted butter, melted
1 teaspoon Dijon mustard
1 teaspoon honey, optional
½ teaspoon garlic powder
½ teaspoon dried parsley
¼ teaspoon onion powder
A small pinch of salt

If you’re using biscuits rather than rolls, choose biscuits that are sturdy enough to hold the filling without falling apart. Homemade biscuits work beautifully, but refrigerated biscuits can make this recipe even faster.

Step-by-Step Method

Step 1: Prepare the Oven

Preheat your oven to 350°F (175°C).

Lightly grease a 9×13-inch baking dish or another baking dish large enough to hold the sliders snugly.

Keeping the sliders close together helps them stay soft on the sides while the tops become beautifully golden.

Step 2: Prepare the Biscuit Base

If you’re using pre-baked biscuits, carefully slice each one horizontally, creating a top and bottom.

If you’re using refrigerated biscuit dough, bake the biscuits according to the package directions first, then allow them to cool slightly before slicing.

Arrange the bottom halves in your prepared baking dish.

Step 3: Add a Flavorful Spread

For an extra layer of flavor, spread a thin layer of mustard over the biscuit bottoms.

You can also combine mayonnaise and mustard for a creamy spread. If you’re serving these to children or guests who don’t enjoy mustard, simply leave it out.

The spread shouldn’t be too thick because you want the ham and cheese to remain the stars of the sandwich.

Step 4: Layer the Ham

Place the ham evenly over the biscuits.

Fold each slice slightly instead of laying it completely flat. This creates little layers throughout the sliders and gives the finished sandwiches a more substantial texture.

You can use deli ham, honey ham, smoked ham, or leftover baked ham. Thinly sliced ham works particularly well because it warms quickly and distributes evenly.

Step 5: Add the Cheese

Arrange the cheese over the ham, making sure it reaches close to the edges.

Swiss cheese gives the sliders a classic savory flavor, while cheddar creates a sharper, richer result. Provolone melts smoothly and has a mild flavor, and mozzarella gives you plenty of stretchy cheese.

For an especially cheesy version, use a combination of two cheeses.