Easy Fajita Chicken Breasts Casserole: A Flavorful One-Pan Dinner

If you’re looking for a dinner that is full of flavor, simple to prepare, and guaranteed to please the whole family, the Easy Fajita Chicken Breasts Casserole should be at the top of your list. This dish combines the smoky spices of fajitas with tender baked chicken, colorful vegetables, and a layer of melted cheese—all in one casserole dish. Best of all, it’s a meal that feels special without requiring hours in the kitchen.

Why You’ll Love This Recipe

One-dish wonder: Less cleanup, more enjoyment.
Bold flavors: Inspired by Tex-Mex fajitas with peppers, onions, and seasoning.
Customizable: Add rice, beans, or serve with warm tortillas.
Perfect for meal prep: Stores well in the fridge and reheats beautifully.

Ingredients You’ll Need

3–4 boneless chicken breasts
1 red bell pepper, sliced into strips
1 yellow bell pepper, sliced into strips
1 green bell pepper, sliced into strips
1 medium onion, sliced thin
2 tablespoons olive oil
2 teaspoons chili powder
1 teaspoon paprika
1 teaspoon ground cumin
½ teaspoon garlic powder
½ teaspoon onion powder
½ teaspoon salt
¼ teaspoon black pepper
1 cup shredded Mexican blend or cheddar cheese
½ cup sour cream (optional for serving)
Fresh cilantro and lime wedges for garnish

Step-by-Step Method

Step 1: Prepare the Chicken

Start by preheating your oven to 375°F (190°C). Lightly grease a casserole dish with olive oil or non-stick spray. Lay the chicken breasts flat in the dish. If the breasts are very thick, consider slicing them in half lengthwise so they cook evenly.

Step 2: Season Generously

In a small bowl, mix together the chili powder, paprika, cumin, garlic powder, onion powder, salt, and black pepper. Drizzle olive oil over the chicken and sprinkle the seasoning mix evenly on both sides of each breast.

Step 3: Add the Vegetables

Scatter the sliced peppers and onions over and around the chicken. These vegetables will soften as they bake, soaking up the seasoning and releasing their juices to keep the chicken tender.