Mac and Cheese Meatloaf Casserole Ingredients

May be an image of shepherd's pie and text that says 'MAC AND CHEESE MEATLOAF CASSEROLE -1lb ground beef -1cup bread crumbs -2eggs eggs'

Step 2: Cook the Macaroni

  1. Bring a large pot of salted water to a boil.
  2. Add the elbow macaroni and cook according to package instructions until al dente.
  3. Drain and set aside.

Step 3: Make the Cheese Sauce

  1. In a medium saucepan, melt the butter over medium heat.
  2. Whisk in the flour and cook for 1-2 minutes to remove the raw flour taste.
  3. Slowly pour in the milk while whisking constantly to prevent lumps.
  4. Cook until the mixture thickens, about 4-5 minutes.
  5. Stir in the shredded cheese until fully melted and smooth. Season with salt, pepper, and smoked paprika.
  6. Add the cooked macaroni to the cheese sauce and mix well.

Step 4: Assemble the Casserole

  1. Preheat your oven to 375°F (190°C).
  2. Grease a 9×13-inch baking dish lightly with butter or cooking spray.
  3. Spread half of the mac and cheese in the bottom of the dish.
  4. Carefully layer the meatloaf mixture on top of the macaroni, spreading it evenly.
  5. Top the meatloaf with the remaining mac and cheese.
  6. If desired, sprinkle additional shredded cheese and breadcrumbs on top for a golden, crispy finish.

Step 5: Bake

  1. Cover the casserole loosely with aluminum foil.
  2. Bake in the preheated oven for 45 minutes.
  3. Remove the foil and bake for an additional 15 minutes until the top is bubbly and slightly browned.

Step 6: Serve

  1. Allow the casserole to rest for 5-10 minutes after removing it from the oven.
  2. Cut into generous squares or scoops.
  3. Serve warm with a simple green salad or steamed vegetables for a complete meal.

Tips for Success

  • Cheese Variations: Add pepper jack or Gruyère for a richer flavor.
  • Make Ahead: Assemble the casserole a day ahead, refrigerate, and bake when ready.
  • Spice it Up: Add a pinch of cayenne pepper to the meatloaf mixture for a subtle kick.

This Mac and Cheese Meatloaf Casserole is comfort food at its finest: creamy, cheesy, and meaty, all in one dish. It’s perfect for feeding a crowd or enjoying leftovers that taste even better the next day.


If you want, I can also create a visual step-by-step guide with pictures for this casserole, so it’s easier to follow in the kitchen.

Do you want me to do that?

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