Mac and Cheese Meatloaf Casserole

May be an image of shepherd's pie and text that says 'MAC AND CHEESE MEATLOAF CASSEROLE -1lb ground beef -1cup bread crumbs -2eggs eggs'

Step 4: Prepare the Meatloaf Mixture

  1. In a large bowl, combine ground beef, ground pork (if using), chopped onion, minced garlic, breadcrumbs, milk, egg, ketchup, Worcestershire sauce, salt, pepper, and paprika.
  2. Mix gently until all ingredients are just combined. Overmixing can make the meatloaf tough.

Step 5: Assemble the Casserole

  1. Spread half of the mac and cheese in the bottom of the prepared baking dish.
  2. Carefully layer the meatloaf mixture on top, pressing it gently to form an even layer.
  3. Spread the remaining mac and cheese over the meatloaf.

Step 6: Add Topping

Sprinkle the shredded cheddar cheese over the top. For a golden, crunchy finish, mix the breadcrumbs with melted butter and sprinkle them over the cheese layer.


Step 7: Bake

Cover the casserole loosely with aluminum foil and bake for 30 minutes. Remove the foil and bake for an additional 15–20 minutes until the top is golden brown and the meatloaf is cooked through (internal temperature should reach 160°F / 71°C).


Step 8: Serve

Let the casserole rest for 5–10 minutes before slicing. This helps the layers set and makes serving easier. Serve hot, perhaps with a simple green salad or steamed veggies on the side for balance.


Tips for Success

  • Cheese Variety: Mix cheddar with Monterey Jack or mozzarella for extra gooeyness.
  • Meatloaf Moisture: Add a tablespoon of tomato sauce or finely grated zucchini to keep the meatloaf moist.
  • Make Ahead: Prepare the casserole a day in advance and bake it fresh. This allows flavors to meld beautifully.
  • Spice it Up: Add a pinch of cayenne pepper or smoked paprika to the meatloaf for a subtle kick.

Final Thoughts

The Mac and Cheese Meatloaf Casserole is comfort food at its finest—a satisfying fusion of creamy, cheesy pasta and savory meatloaf. Its layered texture, rich flavor, and golden cheesy top make it an instant family favorite. Once you try it, this casserole will likely become a staple for cozy dinners or special occasions when you want something indulgent and heartwarming.


If you want, I can also create a simplified, one-page “quick recipe card” version for this casserole, perfect for printing or keeping in the kitchen for easy reference.

Do you want me to make that?

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